This is a form of poisoning or chemical imbalance, that doesnt affect fish already in the tank because there are fish in there for months that are doing fine, but only new entrants die within hours. Tangs die within 24 hours and other species either survive or die over a very long period of time.
At first I thought it was my introduction regime, but it cant be that because I drip new fish for hours before they are introduction. Its not a sudden swing in parameters between QT and DT because I checked that as well.
After 17 years in this hobby I am stumped and about to throw in the towel which is very sad.
Firstly, very sorry to hear about your losses, I can only imagine what you are going through.
Secondly, how are you feeding your foods? Are you defrosting frozens directly in your tank or throwing in live food liquid and sundry into the tank?
Reason why I ask this is because I have read stories about frozen foods containing harmful bacteria. When you initially add the foods without defrosting you add these bacteria to the tank. Fish that are already in the tank build up a resistance to them over time whereas any new additions cannot handle them and end up dying.
How old are your uv lamps? (On phone so can't check thread properly).
Speculation but Could be a possibility?
I hope you get to the bottom of this issue soon!