This is basically all the Info I could find..any body try this yet with sps and clams
Spots & Velvets Salt is well tolerated by invertebrates, and it is not necessary to remove corals from the aquarium during the treatment.
http://www.marineaquariumsa.com/showthread.php?t=37513Seachem Cupramine is the best medication for velvet IME (and it's also usable with most copper sensitive fish). But as they others said, once a fish gets that heavily infected then it's often too late. This is why medicated quarantine is a good idea.
Unfortunately this doesn't put a persons mind to rest..regarding Reef Safe..problem is i cant catch the fish so it has to be in tank medication
http://www.seachem.com/Products/product_pages/Cupramine.htmlCupramine™ is easily removable with chemical filtration. It is highly effective and safe in freshwater as well as marine water..
Prodibio spots & Velvet is perfectly reef safe used it on a couple of full SPS tanks with clams and invertebrates. no defects what so ever. no Paragaurd in reef tank no.
I have used this in my tank but I do not have any SPS or clams. I have softies and some torches. I do have shrimp and snails. I did not read the instructions properly. Make very sure that you have lots of oxygen in the tank. Put in extra air stones. I lost quite a few fish due to lack of oxygen. They were not infected when they died. Only my clowns had some white spot. I have not had any more white spot after completing the treatment. This was my experience and does not mean that you will have or not have any problems using it.
Prodibio spots and velvets is 100% reef safe.. Heard to much bad stuff about artemiss and herbtana..